We do not realize the mechanisms of biological aging or the reasons for aging are the limits of the estimated averages life expectancy of people are very empirical. The forces of natural selection with age, as in natural populations, few people survive beyond the age of reproduction. In recognition of these ideas, some would suggest an antagonistic pleiotropy hypothesis that the genes of a disadvantage in a population is not necessary to the reproductive phase, after which take place occur at the population can get. The environment is hostile, and individuals compete for resources.
It is a better scheme for the survival of organisms to commit resources in a line of growth and reproduction in adulthood, rather than the long-term maintenance of the soma. Designed so the body has a soma with a survival time is limited to one advantage over those who try to maintain the soma indefinitely. The disposable soma theory clearly explains the early origins of aging in animals.
Finch has examined the relationship between lifespan and fertility, and between life and hostility of the environment for a number and species of plants and animals. For many years after the Gompertz or Gompertz hazard function, which first formulated by Benjamin Gompertz in 1825, it seemed better to describe the relationship between age and mortality of man. This relationship reflects the increasing probability of death with the age of the population. The model should describe the impact on the mortality of the internal mechanisms of the physiological changes in the functioning of the genetic age limits. You must also specify how processes develop genetically limited to age, develop as a result of stochastic effects of environmental stress, and how the functioning of the physiological mechanisms in response to the agency and change the internal environment resulting from the impact.
Gompertz formulation can not accept the characterization of the relationship between mortality and aging in the human population has been evident in recent years. Data from the U.S. population over the last 25 years have shown that the major change that life carries the segment of the population was over 50-year period. There is currently a realistic estimate of life expectancy for men? The most reliable estimate of life expectancy at birth is about 85 years.
Only recently, the continuing trend of increasing life expectancy over 50 years shows no evidence that life is approaching an upper limit. Since we have very recent data suggest that is executed, the biological limit to life. This is a hypothetical example of a survival curve over 50 years, it might today a population whose life expectancy at birth of 80 years to draw a curve for a population life expectancy at birth in 2050 compared to 100 years.
The second curve shows signs of compression of mortality. Rectangularisation results extend the phase of the curve, in which some deaths decreases sharply by a relatively short phase, where the mortality rate is high and the number of survivors is followed. The survival curve rectangularisation suggests that the life expectancy of the population is approaching an upper limit. The combined trends of increased life expectancy at birth and life expectancy has more than 50 years, say much that has the risk of fatalities in recent years, back into the past 2030 years.
