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Obsessive Compulsive Disorders Treatment with Drugs

Obsessive Compulsive Disorders Treatment
Because there are no placebo-controlled treatment studies of Obsessive Compulsive Disorders in elderly, Obsessive Compulsive Disorders treatment guidelines are generally extrapolated from studies of younger populations and case reports of treated elderly. Selective serotonin reuptake inhibitors (SSRIs) are the drugs of first choice for OCD. (more…)

Body Fat Distribution and Caloric Restriction Principles

Body Fat Distribution

Not all body fat is equally bad for your health. It is widely known that body fat distribution is extremely important. There is increasing evidence for the deleterious effects of Visceral Fat on aging. Waist-to-hip ratio (WHR) is an epidemiological tool that demonstrates a correlation between Visceral Fat and development of diabetes mellitus, stroke, coronary artery disease, and mortality. This ratio is easily determined by dividing the measurement of waist circumference by hip circumference. (more…)

12 Lead Electrocardiogram (ECG) to Detect Cardiac Arrhythmias and Sudden Death

Several clinical tools are available for identification of patients at risk of cardiac arrhythmias or its consequences that may benefit from interventions to reduce morbidity and risk of sudden death. These include noninvasive tests, such as a standard (more…)

Stroke Prevention in Atrial Fibrillation

Atrial Fibrillation affects approximately 2.3 million people in the United States and is the most common rhythm disorder among U.S. patients hospitalized with a primary diagnosis of an cardiac arrhythmia. The median age of Atrial Fibrillation patients is 75 years; 84% are older than 65 years. Pooled data from studies of chronic Atrial Fibrillation in North America, Britain, and Iceland suggest a prevalence of 0.5% to 1% in the general population. (more…)

Progeroid Syndromes - Gene Variants Related with Premature Aging

Progeroid Syndromes
Some genetic mutations appear to accelerate certain features of aging only within a single tissue. There are a very large number of these conditions, which might be referred to as unimodal progeroid syndromes. Here only three examples are considered: one that has a major impact on sun-exposed skin, one that results in an early onset of the most common form of dementia alzheimer, Alzheimer’s disease, and another that results in early-onset Parkinson’s disease. (more…)

Special Considerations Obesity in the Elderly: Illnesses, Frailty, Morbidity

obesity elderly
Obesity in the elderly is a major health crisis facing our population that may predispose the elderly to the same adverse health outcomes facing the younger, obese population. However, several studies have suggested that the risk of obesity on life span is less in the elderly and may even become insignificant. However, these studies have found an increase in disability in older subjects with obesity. (more…)

Female Androgen Deficiency Syndrome (FADS)

The prevalence of sexual dysfunction in women approaches 43%, and age is an important correlate. The underlying etiology of sexual dysfunction in women is complex. Nevertheless, hormonal changes such as loss of estrogens and androgens contribute significantly to some of the sexual difficulties experienced by aging women. (more…)

Pharmacokinetics Metabolism and Changes Associated with Aging


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There are several important changes in pharmacokinetics metabolism associated with aging that predispose the elderly to increased risk of druginduced side effects including cardiac arrhythmia.

First, advanced age is accompanied by a decrease in overall body weight, total body water, lean body mass, and intravascular volume, resulting in a greater volume of distribution (V d ), which is defined by the drug dose divided by drug plasma concentration (V d = dose/concentration). The reduced distribution volume will, therefore, lead to a higher drug concentration after a given dose in the elderly compared to the younger population. (more…)

Pain in Elderly: Definition and Dimension

pain in elderly
As people growing older or become elderly, several health risks and health complications and problem may happened because the natural degeneration of human systems and organ. When you are growing older and become member of elderly population, some complications associated with general body aches and pains may occur. (more…)

Rheumatoid Arthritis: Symptoms & Treatments

Rheumatoid Arthritis affects approximately 1% of the world’s population. Rheumatoid Arthritis
is a chronic, multisystem, autoimmune, and inflammatory disorder that involves peripheral joints in a symmetric distribution. The potential of the synovial inflammation to cause cartilage damage and bone erosions and subsequent changes in joint integrity is the feature of the disease. (more…)

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