Aging begins before we are born, is a lifelong process and continues throughout life. Throughout the life course, differing life experiences influence our capabilities and well-being in our later years. The functional capacity of our biological systems increases during the first years of life, reaches its peak in early adult-hood and naturally declines thereafter. Throughout most countries (but not all), persons experience a long childhood and a long old age. These two lengthy developmental spans have provided great utility. Throughout history, it has enabled older persons to educate the younger and pass on values to them. (more…)

The prevalence of sexual dysfunction in women approaches 43%, and age is an important correlate. The underlying etiology of sexual dysfunction in women is complex. Nevertheless, hormonal changes such as loss of estrogens and androgens contribute significantly to some of the sexual difficulties experienced by aging women. (more…)

The accurate diagnosis of endocrine dysfunction in the elderly requires a high index of suspicion. Signs and symptoms of hormone deficiency or excess may be absent. When such signs and symptoms are present, coexisting malnutrition or chronic disease may often make their interpretation difficult. (more…)

Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocrine function. Several mechanisms interact in most systems to bring about the observed changes. Aging is associated with anatomic changes of the endocrine glands. In addition, with age, changes in hormone replacement secretion occur, including alterations in circadian or seasonal biorhythms, changes in pulsatile frequency or amplitude of growth hormone secretion, as well as absolute changes in mean serum hormonal levels. The three main hormone systems that show decline with age are the gonadal hormones (menopause and andropause), the adrenal steroids DHEA and DHEA-S (adrenopause), and the GH/IGF-1 axis (somatopause). (more…)

For trained physicians, aging is often defined by the age-related diseases and disorders people experience as they grow older. In fact, aging is often portrayed as a disease that is amenable to treatment, just like any other elderly chronic diseases that physicians are trained to diagnose and treat. This is not an unexpected view of aging given the Western disease-oriented model of medical education. Examples of the conditions that anti-aging practitioners endeavor to treat or postpone include cardiovascular disease, cancer, sensory impairments, muscle and bone loss, loss of skin elasticity, and decline in sexual activity in elderly function. (more…)

Involuntary weight loss is the result of many chronic progressive diseases, often leading to diminished lean body mass, frailty, susceptibility to illness, and increased mortality. Various anabolic agents have been used to combat weight loss with mixed results. Similar to the frustration experienced by advocates of weight loss in the obese, none of the pharmacological appetite stimulants available at the current time have been uniformly successful in combating involuntary weight loss in the elderly population. (more…)

Osteoporosis is disease affecting the bones, making them fragile and prone to fracture. Osteoporosis is defined as a systemic skeletal disease characterized by low bone mass and microarchitectural deterioraton of bone mass tissue, with a consequent increase in bone fragility and susceptibility to fracture. Osteoporosis is a condition characterized by mass loss of the normal density of bone. (more…)

Potential benefits of T treatment in older men must be weighed against risks of adverse effects. In young hypogonadal men, physiological T replacement is low risk. In older men, risk–benefit ratios may be less advantageous. Minor adverse effects of T treatment include fluid retention, erythrocytosis, and sleep apnea, problems that may be more common in old men. Of greater concern are possible increases in atherosclerosis and greater risk of prostate cancer. (more…)

As you probably know, sex hormone in women is declining with age. Men also experiencing the same, even though the declining rate is not as steep drop like women menopause. But the effect is substantial in well being and fertility. Until recent years, there has been a lot concern about the subject of testosterone levels in men. Andropause as the name suggest, is declining 1% per year of testosterone levels hormone for men age over 30 years. This significantly put those men group in risk of having disease-syndromes related to andropause. (more…)

When approaching menopause or during post-menopause period, most women suffered from menopausal symptoms irritability like hot flashes, vaginal dryness, urination difficulty, night sweats and osteoporosis.

All symptoms above were as the result of your body reducing hormone production as you are aging. It may start as early as age 25 for women, and hormone level production reduce significantly until menopause period. (more…)