Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocrine function. Several mechanisms interact in most systems to bring about the observed changes. Aging is associated with anatomic changes of the endocrine glands. In addition, with age, changes in hormone replacement secretion occur, including alterations in circadian or seasonal biorhythms, changes in pulsatile frequency or amplitude of growth hormone secretion, as well as absolute changes in mean serum hormonal levels. The three main hormone systems that show decline with age are the gonadal hormones (menopause and andropause), the adrenal steroids DHEA and DHEA-S (adrenopause), and the GH/IGF-1 axis (somatopause). (more…)
Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocr ...
The accurate diagnosis of endocrine dysfunction in the elderly requires a high index of suspicion. Signs and symptoms of hormone de ...
The systemic benefits of exogenous Growth Hormone therapy in the healthy elderly remain unclear and controversial. Studies have ...
The prevalence of sexual dysfunction in women approaches 43%, and age is an important correlate. The underlying etiology of sexual ...
When approaching menopause or during post-menopause period, most women suffered from menopausal symptoms irritability like ...
Involuntary weight loss is the result of many chronic progressive diseases, often leading to diminished lean body mass, frailty, susceptibility to illness, and increased mortality. Various anabolic agents have been used to combat weight loss with mixed results. Similar to the frustration experienced by advocates of weight loss in the obese, none of the pharmacological appetite stimulants available at the current time have been uniformly successful in combating involuntary weight loss in the elderly population. (more…)
The systemic benefits of exogenous Growth Hormone therapy in the healthy elderly remain unclear and controversial. Studies have ...
When approaching menopause or during post-menopause period, most women suffered from menopausal symptoms irritability like ...
Potential benefits of T treatment in older men must be weighed against risks of adverse effects. In young hypogonadal men, physiolo ...
Obesity results from an imbalance between caloric consumption and caloric expenditure over a prolonged period. Weight gain occurs w ...
As you probably know, sex hormone in women is declining with age. Men also experiencing the same, even though the declining rat ...
Potential benefits of T treatment in older men must be weighed against risks of adverse effects. In young hypogonadal men, physiological T replacement is low risk. In older men, risk–benefit ratios may be less advantageous. Minor adverse effects of T treatment include fluid retention, erythrocytosis, and sleep apnea, problems that may be more common in old men. Of greater concern are possible increases in atherosclerosis and greater risk of prostate cancer. (more…)
As you probably know, sex hormone in women is declining with age. Men also experiencing the same, even though the declining rat ...
The systemic benefits of exogenous Growth Hormone therapy in the healthy elderly remain unclear and controversial. Studies have ...
Animal studies support a cancer-promoting role for fat, and in humans, epidemiological data strongly suggest that dietary fat i ...
Cancer occurrence rates in a period of time for a given population is expressed in various ways. The incidence rate is a direct mea ...
The reduced physiological reserve after the one quoted above includes anatomical changes associated with aging, functional resp ...
As you probably know, sex hormone in women is declining with age. Men also experiencing the same, even though the declining rate is not as steep drop like women menopause. But the effect is substantial in well being and fertility. Until recent years, there has been a lot concern about the subject of testosterone levels in men. Andropause as the name suggest, is declining 1% per year of testosterone levels hormone for men age over 30 years. This significantly put those men group in risk of having disease-syndromes related to andropause. (more…)
The accurate diagnosis of endocrine dysfunction in the elderly requires a high index of suspicion. Signs and symptoms of hormone de ...
Potential benefits of T treatment in older men must be weighed against risks of adverse effects. In young hypogonadal men, physiolo ...
The prevalence of sexual dysfunction in women approaches 43%, and age is an important correlate. The underlying etiology of sexual ...
Involuntary weight loss is the result of many chronic progressive diseases, often leading to diminished lean body mass, frailty, su ...
The systemic benefits of exogenous Growth Hormone therapy in the healthy elderly remain unclear and controversial. Studies have ...