Certain enzymes and many small water-soluble and lipid-soluble molecules can intercept and destroy free radicals and other reactive oxygen species (ROS). Important components of cellular enzymatic protection include catalase, superoxide dismutase (Mn, Cu/Zn, extracellular), glutathione peroxidase, glutathione reductase, glutathione S-transferase, glucose-6-phosphate dehydrogenase, and thioredoxin reductase. (more…)
There are endogenous and external sources of ‘natural’ oxygen free radicals and other ROS. Thus, under normal conditions endogenous ...
An increase in the concentration of free radicals, measured using electron spin resonance (ESR) spectroscopy, can reflect the degre ...
The Late Biological Effects of Ionizing Radiation Exposure to ionizing radiation results in an increase in oxidative damage to DNA, ...
Cellular Response to Oxidative Stress and Sensitivity of Transcription Factors to ROS That Determine the Response. It is establishe ...
If we want less wrinkles, we need to start as early in life as possible. What do we need to do? There are a number of important ...
Cellular Response to Oxidative Stress and Sensitivity of Transcription Factors to ROS That Determine the Response. It is established that control of gene expression is required for proper response to stress and that transcription factors play a crucial role in regulating these processes. Modification of the redox state of certain transcription factors can contribute to or inhibit the formation of specific complexes between these factors and their cognate DNA elements in mammalian cells. This mechanism is similar to the mechanism of regulation of gene expression in response to oxidative stress in bacteria through a change in the DNA-binding specificity of the bacterial transcriptional regulatory protein, OxyR. (more…)
Mutations that extend lifespan in invertebrates typically render the animals resistant to multiple forms of lethal injury, whether ...
An increase in the concentration of free radicals, measured using electron spin resonance (ESR) spectroscopy, can reflect the degre ...
There are endogenous and external sources of ‘natural’ oxygen free radicals and other ROS. Thus, under normal conditions endogenous ...
The Late Biological Effects of Ionizing Radiation Exposure to ionizing radiation results in an increase in oxidative damage to DNA, ...
Reactive radicals of nitrogen (nitric oxide and derivatives such as peroxynitrite) and of oxygen (superoxide anion, hydrogen peroxi ...
The regulation of fluid balance is crucial to survival. Approximately 9 L of fluid enters the gastrointestinal tract per day. Of that amount, about 2 L is ingested by mouth. The remaining 7 L consists of fluids secreted by the various gastrointestinal organs. Ninety eight percent of the total amount of fluid that enters the gastrointestinal tract is reabsorbed in the small intestine and the colon. (more…)
After appropriate digestion of nutrients, the function of the gastrointestinal tract is to absorb these nutrients so they may be us ...
The motility of the gastrointestinal tract is complex, and normal motility is critical to proper secretion and digestion. In order ...
The accumulative waste theory of aging, also known as the waste accumulation or garbage accumulation theory of aging, proposes ...
The reduced physiological reserve after the one quoted above includes anatomical changes associated with aging, functional resp ...
Doctors frequently have the patients need their dietary advice. As a doctor, I ‘ve talked to many patients over the huge amount ...
There are many options of foods and supplements that we can choose to slow the aging process. Not only it helps maintain our youthful look, it helps us live a life of quality, as we advance in life. Many of aging problems is associated with oxidants that we found in our daily lives. Some oxidants substances are know for their ability to accelerate the aging process. Many of them can be derived from food and dietary anti aging supplements. The important point is we can do much to help slow the pace and intensity of aging process. (more…)
It is truly an astounding promised by products that claimed can help slowing aging. There were plenty of such products and yo ...
Recent studies have shown that most anti-wrinkle creams do not produce more than 10% improvement in the appearance of a person. How ...
Ever wonder how to remove wrinkles and regain the complexion you once had? Although it's hard to eliminate wrinkle all together ...
The lines in my forehead were not that deep, but I was starting to look like my mother. So, I changed my hairstyle to hide them ...
It is always important in the treatment of dementia to have clear therapeutic goals established in partnership with the patient and family. Often, the concept of quality of life is an important guide to therapy, as this reflects the values of the individual and his or her family. This section discusses both non-pharmacological and pharmacological treatments of dementia. Remember that non-pharmacological approaches are always appropriate. (more…)
Unfortunately, many dementias are partially or completely biologically irreversible. However, as mentioned previously, it is im ...
The treatment of any person of any age with any degree of cognitive impairment must be individualized. Clearly, if there are underl ...
The principal reversible dementias are metabolic. Hypothyroidism and exposure to industrial or environmental toxins should be c ...
Alzheimer’s disease is a concept in evolution; it is considered by most to be a degenerative brain disease that was first describe ...
It is now almost axiomatic that late-life depression is under detected, under diagnosed, and under treated. Although this basic ...
Recent studies have shown that most anti-wrinkle creams do not produce more than 10% improvement in the appearance of a person. However, some compounds are more efficient compare to other common anti wrinkle products. We will highlight and look further at these specific products. (more…)
For decades, anti aging moisturizers haven't been much different from those designed for fresh young skin people. The primary c ...
Ever wonder how to remove wrinkles and regain the complexion you once had? Although it's hard to eliminate wrinkle all together ...
Is there really an anti wrinkle firming cream that is effective for erasing the lines that you have developed over the years? I ...
Your eyes are what people focus on when they first meet you especially with new people. Therefore, you want to have lovely eyes ...
It seems like every time you turn you head, there is another company claiming that their creams are the best anti aging wrinkle ...
When women are reaching the age of 40, they face a difficult dilemma. They have to choose between their skin face and healthy body. It may have been reported on some research that to lose weight in this age easily lead to an aging face. Sagging and not elastic face can be a problem. (more…)
If you followed the anti-aging therapy methods, you may have heard of collagen supplements. These products are available on the mar ...
Many people believe that if you are aging and your face has some damage on them because of this, you can not reverse the aging ...
Let's face it, you would love to have that fresh young skin you had when you were younger? However unless you have been taking ...
Prescription wrinkle creams do work, the problem I have with them is their unpleasant side effects. I prefer to use natural anti wr ...
Are you looking for a neck firming cream to help get rid of all that sagging skin on your neck. The skin on your neck is very t ...
Green tea is widely known as source of good healthy drink. For many, it has become one of popular weight loss programs. People in Asians countries have been drinking green tea for thousands years as a natural remedy for a variety of illness, like headaches and depression. Some studies have shown that green tea compounds play a role in reducing amount of cholesterol absorbed by the body, eliminated the increase in the amount of cholesterol, and increase your blood cholesterol is stored in the liver. This is the other benefit of how tea can affect in reducing cholesterol levels. (more…)
The lines in my forehead were not that deep, but I was starting to look like my mother. So, I changed my hairstyle to hide them ...
Ever wonder how to remove wrinkles and regain the complexion you once had? Although it's hard to eliminate wrinkle all together ...
There are new strategies to address the 3 critical factors for body health: blood sugar, insulin and inflammation. These formul ...
No matter where you live and in what circumstances, it's evident that ours is a planet that has been damaged over centuries of ...
In many instances, the symptoms listed below are the result of relatively minor disorders as elderly. However, they can also represent the early signs of serious chronic disease in older adults, and they should be investigated promptly by your doctor. (more…)
Visual impairment among elderly is now a major health care problem. We are living in aging population with 80% of blind people ...
It is estimated that about 6 million Americans over 65 suffer from depression in late life. The sad reality is that 10% are loo ...
Fibromyalgia and myofascial pain (MP) are among the most common musculoskeletal disorders from which older adults suffer. These dis ...
Depression is not a monolithic disorder. Rather, it presents in a variety of syndromes that may vary in severity, length, and ass ...
The majority of older adults who suffer from depression experience lower-level symptoms that do not meet diagnostic criteria fo ...
Green Food is a popular term used to describe young cereal grasses such as barley grass, wheat, rye and oats, before the grass is changed to grain. Cereal grasses have long been cultivated for their energy-dense granules, but change the profile of green cereal plants as they grow up fast. Chlorophyll, protein, antioxidants and vitamins in cereal grasses declines sharply and the amount of cellulose (indigestible fiber) increases. (more…)
Back pain is a real pain in your back! You want relief now but would like to try some natural home remedies before resorting to pre ...
Prevention is the best cure for back pain. If I had practice proper lifting techniques and /or the box I lifted had been proper ...
Ever wonder how to remove wrinkles and regain the complexion you once had? Although it's hard to eliminate wrinkle all together ...
Finding the best anti-aging skin creams, contrary to what most people think, is not that hard. Once you understand your skin an ...
With heart disease risk being the number one cause of death among older Americans, you should pay particular attention to known ...