Although many possible explanations for the mechanism that underlies the Hayflick limit have been proposed, it is still not clear what triggers the irreversible growth arrest seen in cellular senescent. A loss of telomeres, DNA at the end of each chromosome, has been considered an attractive candidate for the senescent trigger. The hypothesis was that a small amount of the telomere at the end of the chromosome (which is linear) is lost at each cell division due to the directionality of DNA polymerase. DNA polymerase can completely replicate one strand of DNA but cannot begin at the very end of the opposite strand. (more…)
Although we have not identified the genes controlling human life span, there is a genetic element called a telomere that clearly re ...
One approach to understanding the senescent growth arrest is to examine the factors that are required for the division of young ...
Hayflick suggested that the aging process was by a biological clock, which includes all living cells, controlled. The study found t ...
Oncogenes are damaged versions of normal genes (‘proto-oncogenes’) that control cell growth and differentiation. It is importan ...
In every population of cells there are three types of cell. The first group consists of cycling cells, which continuously proli ...
By Blogsdna
Cancer is the second leading cause of mortality after heart disease and the leading cause of death among women ages 40 to 79 and men ages 60 to 79. Within the 65+ age group, the population 85 years and older is projected to double from 4.3 million in 2005 million by 2030. Life expectancy has increased. More people are treated successfully after a cancer diagnosis, resulting in a greater prevalence of the elderly living with or developing cancer. It is important for all professionals dealing with the elderly to understand what the disease is and how to deal with it. (more…)
In every population of cells there are three types of cell. The first group consists of cycling cells, which continuously proli ...
Cancer is also called malignant neoplasm. This implies that the growth is a new growth (neoplasm) that if unchecked will kill the h ...
Much of cell death is genetically programmed by the process called apoptosis. In apoptosis, when the cell is damaged, the DNA i ...
Cancer occurrence rates in a period of time for a given population is expressed in various ways. The incidence rate is a direct mea ...
The sequencing of the human genome was begun in 1990 and completed in 2003. The International Human Genome Sequencing Consortiu ...
By Blogsdna
Some researches on relation between exercise and body human health results indicate that in addition to increasing muscle capacity, physical activity can help improve strength, balance, joint mobility, flexibility, agility, the speed with which one walks and physical coordination as a whole. In addition, physical activity has effects favorably on metabolism, blood pressure regulation, and prevention of an excessive increase in weight. (more…)
Prevention is the best cure for back pain. If I had practice proper lifting techniques and /or the box I lifted had been proper ...
As a normal ageing process, as you grow older, you will lose muscle fiber. The composition between fats and muscles in your bod ...
Osteoporosis is disease affecting the bones, making them fragile and prone to fracture. Osteoporosis is defined as a systemic s ...
With heart disease risk being the number one cause of death among older Americans, you should pay particular attention to known ...
Alcohol abuse can be defined as individuals drink more than normal quantity but on regular basis. This habits causes poor healt ...
By Blogsdna
Why do we age and get wrinkles on our skin?
That’s because as we grow older, the elasticity of our skin becomes lower. And the skin loses moisture causing the skin to sag and lines to appear. (more…)
It seems like every time you turn you head, there is another company claiming that their creams are the best anti aging wrinkle ...
Lately you have found yourself avoiding the mirror. The last things you want to see are wrinkles, fine lines, age spots and dry ...
Many people believe that if you are aging and your face has some damage on them because of this, you can not reverse the aging ...
Prescription wrinkle creams do work, the problem I have with them is their unpleasant side effects. I prefer to use natural anti wr ...
"What is the best anti wrinkle product?" and "What are the best home remedies for wrinkles on skin?" are the most common questions ...
By Blogsdna
The first line of defense belongs to a compound in the body called alpha lipoic acid (ALA). You may already know the importance I place on this multitasking, multi protective supplement. But recent studies have shown that it is even more powerful than previously thought.
Alpha lipoic acid is a very powerful antioxidant, anti-inflammatory agent, but additional amounts can be obtained only from (more…)
It is truly an astounding promised by products that claimed can help slowing aging. There were plenty of such products and yo ...
Enzymatic Antioxidants Certain enzymes and many small water-soluble and lipid-soluble molecules can intercept and destroy free ra ...
Anti-aging and age skin care products added with Alpha Hydroxy Acids (AHA) are flooding cosmetic market. Alpha hydroxy acids ar ...
There are many options of foods and supplements that we can choose to slow the aging process. Not only it helps maintain our youthf ...
By Blogsdna
The largest single risk factor for developing cancer is age. The incidence of cancer increases exponentially with age, although death from cancer (cancer mortality) may decline at very old age. The inevitable age-dependent rise in cancer incidence is a feature of multicellular organisms that contain a substantial fraction of mitotic cells. Organisms such as flies and worms are composed primarily of post-mitotic cells, and hence do not develop cancer. (more…)
The sequencing of the human genome was begun in 1990 and completed in 2003. The International Human Genome Sequencing Consortiu ...
The classical view of carcinogenesis was that it was a two-‘hit’ process – initiation (genetic) and promotion (epigenetic). How ...
In every population of cells there are three types of cell. The first group consists of cycling cells, which continuously proli ...
Although many possible explanations for the mechanism that underlies the Hayflick limit have been proposed, it is still not cle ...
Oncogenes are damaged versions of normal genes (‘proto-oncogenes’) that control cell growth and differentiation. It is importan ...
By Blogsdna
In elderly people there is a notable reduction in the capacity to produce new blood cells. Yet, unless there is substantial physiological stress, the number of circulating cells remains fairly constant. Quantitative deficiencies are only apparent when stress produces a demand that exceeds reserve proliferative capacity. Such a demand might occur during an acute infection or after cytotoxic chemotherapy. (more…)
Rheumatoid Arthritis affects approximately 1% of the world’s population. Rheumatoid Arthritis is a chronic, multisystem, autoimmun ...
In many instances, the symptoms listed below are the result of relatively minor disorders as elderly. However, they can also re ...
Dyskeratosis congenita is of special interest to gerontologists because it is caused by a mutation in the gene coding for the ...
The prevalence of sexual dysfunction in women approaches 43%, and age is an important correlate. The underlying etiology of sexual ...
The accumulative waste theory of aging, also known as the waste accumulation or garbage accumulation theory of aging, proposes ...
By Blogsdna
Aging in human is a combination of two ageing processes: development or maturation, and senescence aging or decline. Development or maturation is the positive aspect of aging; humans typically acquire greater wisdom, experience, and expertise in specific fields as they grow older. Senescence aging, on the other hand, (more…)
Back pain is a real pain in your back! You want relief now but would like to try some natural home remedies before resorting to pre ...
Prevention is the best cure for back pain. If I had practice proper lifting techniques and /or the box I lifted had been proper ...
With heart disease risk being the number one cause of death among older Americans, you should pay particular attention to known ...
I've been noticing my body's growing inclination to slow down, how it's starting to get tougher to get off the couch, how it ta ...
By Blogsdna