Some genetic mutations appear to accelerate certain features of aging only within a single tissue. There are a very large number of these conditions, which might be referred to as unimodal progeroid syndromes. Here only three examples are considered: one that has a major impact on sun-exposed skin, one that results in an early onset of the most common form of dementia alzheimer, Alzheimer’s disease, and another that results in early-onset Parkinson’s disease. (more…)
Several gene mutations have been shown to cause Parkinson’s Disease, but they account for a small minority of patients and have n ...
Alzheimer’s disease is a concept in evolution; it is considered by most to be a degenerative brain disease that was first describe ...
Cockayne syndrome is caused by the inheritance of genes that are thought to be of special importance in the repair of DNA withi ...
Unfortunately, many dementias are partially or completely biologically irreversible. However, as mentioned previously, it is im ...
Dyskeratosis congenita is of special interest to gerontologists because it is caused by a mutation in the gene coding for the ...
The prevalence of sexual dysfunction in women approaches 43%, and age is an important correlate. The underlying etiology of sexual dysfunction in women is complex. Nevertheless, hormonal changes such as loss of estrogens and androgens contribute significantly to some of the sexual difficulties experienced by aging women. (more…)
When approaching menopause or during post-menopause period, most women suffered from menopausal symptoms irritability like ...
Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocr ...
As you probably know, sex hormone in women is declining with age. Men also experiencing the same, even though the declining rat ...
Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocr ...
The accurate diagnosis of endocrine dysfunction in the elderly requires a high index of suspicion. Signs and symptoms of hormone de ...