Obsessive-compulsive disorder (OCD) is a common neuropsychiatric condition that is frequently unrecognized and untreated, resulting in significant personal suffering and functional impairment. This article reviews the current state of knowledge of OCD epidemiology, clinical features and natural history, differential Obsessive-compulsive disorder diagnosis, and Obsessive Compulsive Disorders treatment options, focusing on how Obsessive Compulsive affects elderly. (more…)
Only about 5–12% of people attending specialty Obsessive Compulsive Disorders OCD clinics are 60 years or older. However, OCD i ...
Because there are no placebo-controlled treatment studies of Obsessive Compulsive Disorders in elderly, Obsessive Compulsive Di ...
Compulsive hoarding disorder consists of three components: acquiring a large number of possessions, storing of items and not di ...
Research indicates that anxiety symptoms are more prevalent in elderly people than in any other age group, occurring at about t ...
Cognitive-Behavioral Interventions Research documenting the efficacy of Cognitive-Behavioral Interventions in treating the psyc ...
Neurocardiogenic Vasovagal syncope is more common in younger patients but also should be considered in elderly patients with unexplained syncope. Although the triggering mechanisms are complex and may differ among young and elderly patients, the efferent responses generally can be categorized as cardioinhibitory (pauses of = 3 seconds or heart rate <40 beats per minute for more than 10 seconds), vasodepressor (systolic blood pressure falls by 50 mm Hg or more without symptoms or 30 to 50 mm Hg with symptoms of syncope or presyncope, and the heart rate does not decrease by more than 10%), (more…)
Carotid sinus hypersensitivity ( more than 3-second pause or a decrease in systolic blood pressure = 50 mm Hg during carotid sinus ...
Aging is associated with progressive fibrosis of the sinoatrial node and AV conduction system, resulting in bradycardia, which may ...
Pacemaker therapy is indicated in patients with symptomatic bradycardia (syncope, presyncope, dyspnea, and exercise intolerance) co ...
Results from several recently completed trials have important implications for the primary prevention of Sudden Cardiac Death Preve ...
There are intrinsic changes in the cardiac pacemaker cells and the cardiac conduction system associated with aging, which increase ...
In older patients without apparent cardiovascular disease, the number of cardiac myocytes declines, while residual myocytes enlarge. Concurrently, there is an increase in elastic and collagenous tissue in all parts of the interstitial matrix and conduction system with advancing age. (more…)
Supraventricular Tachyarrhythmia The principles of drug and non-drug management of supraventricular tachyarrhythmia (SVT) are si ...
Results from several recently completed trials have important implications for the primary prevention of Sudden Cardiac Death Preve ...
Several clinical tools are available for identification of patients at risk of cardiac arrhythmias or its consequences that may ben ...
There are intrinsic changes in the cardiac pacemaker cells and the cardiac conduction system associated with aging, which increase ...
Cardiac Resynchronization Therapy improves functional capacity and quality of life in patients with persistent class III and IV hea ...
Atrial Fibrillation affects approximately 2.3 million people in the United States and is the most common rhythm disorder among U.S. patients hospitalized with a primary diagnosis of an cardiac arrhythmia. The median age of Atrial Fibrillation patients is 75 years; 84% are older than 65 years. Pooled data from studies of chronic Atrial Fibrillation in North America, Britain, and Iceland suggest a prevalence of 0.5% to 1% in the general population. (more…)
Cardiac Resynchronization Therapy improves functional capacity and quality of life in patients with persistent class III and IV hea ...
Supraventricular Tachyarrhythmia The principles of drug and non-drug management of supraventricular tachyarrhythmia (SVT) are si ...
Pacemaker therapy is indicated in patients with symptomatic bradycardia (syncope, presyncope, dyspnea, and exercise intolerance) co ...
Results from several recently completed trials have important implications for the primary prevention of Sudden Cardiac Death Preve ...
In older patients without apparent cardiovascular disease, the number of cardiac myocytes declines, while residual myocytes enlarge ...
Results from several recently completed trials have important implications for the primary prevention of Sudden Cardiac Death Prevention (Table below). In patients with coronary artery disease, prior myocardial infarction, and ejection fraction of 30% or less, a survival benefit was found with prophylactic implantation of a cardioverter defibrillator compared with medical therapy (MADIT-II). In the MADIT-II trial, benefits in patients with preexisting left bundle branch block were more pronounced. In the Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT), an ICD was associated with improved survival compared with amiodarone or medical therapy in patients with class II or III heart failure symptoms and an ejection fraction of 35% or less, and the benefit was evident in patients with or without ischemia (48%). (more…)
Supraventricular Tachyarrhythmia The principles of drug and non-drug management of supraventricular tachyarrhythmia (SVT) are si ...
Cardiac Resynchronization Therapy improves functional capacity and quality of life in patients with persistent class III and IV hea ...
Several clinical tools are available for identification of patients at risk of cardiac arrhythmias or its consequences that may ben ...
In older patients without apparent cardiovascular disease, the number of cardiac myocytes declines, while residual myocytes enlarge ...
Aging is associated with progressive fibrosis of the sinoatrial node and AV conduction system, resulting in bradycardia, which may ...
Cancer occurrence rates in a period of time for a given population is expressed in various ways. The incidence rate is a direct measure of the probability of developing cancer and is usually expressed per year. Incidence rates may be crude (all ages) or age specific. Since cancer is very age dependent, age specific rates are usually more informative. Cancer in elderly is more prevalent compare to cancer in younger age. When comparing population groups with different age distributions (such as the United States vs. China), the incidence rate should be age adjusted by multiplying each age-specific rate by the percent of individuals in a population with the same ages and then summing these to produce a single value. For etiological studies, incidence rates tend to be more informative than mortality rates, as they identify all diagnosed cases. (more…)
Cancer is the second leading cause of mortality after heart disease and the leading cause of death among women ages 40 to 79 and me ...
Animal studies support a cancer-promoting role for fat, and in humans, epidemiological data strongly suggest that dietary fat i ...
Obsessive-compulsive disorder (OCD) is a common neuropsychiatric condition that is frequently unrecognized and untreated, resul ...
The largest single risk factor for developing cancer is age. The incidence of cancer increases exponentially with age, although ...
Potential benefits of T treatment in older men must be weighed against risks of adverse effects. In young hypogonadal men, physiolo ...
Cancer is the second leading cause of mortality after heart disease and the leading cause of death among women ages 40 to 79 and men ages 60 to 79. Within the 65+ age group, the population 85 years and older is projected to double from 4.3 million in 2005 million by 2030. Life expectancy has increased. More people are treated successfully after a cancer diagnosis, resulting in a greater prevalence of the elderly living with or developing cancer. It is important for all professionals dealing with the elderly to understand what the disease is and how to deal with it. (more…)
In every population of cells there are three types of cell. The first group consists of cycling cells, which continuously proli ...
Cancer is also called malignant neoplasm. This implies that the growth is a new growth (neoplasm) that if unchecked will kill the h ...
Much of cell death is genetically programmed by the process called apoptosis. In apoptosis, when the cell is damaged, the DNA i ...
A single drug can shrink or cure human breast, ovary, colon, bladder, brain, liver, and prostate tumors that have been transplanted ...
Cancer occurrence rates in a period of time for a given population is expressed in various ways. The incidence rate is a direct mea ...
The prevalence of sexual dysfunction in women approaches 43%, and age is an important correlate. The underlying etiology of sexual dysfunction in women is complex. Nevertheless, hormonal changes such as loss of estrogens and androgens contribute significantly to some of the sexual difficulties experienced by aging women. (more…)
When approaching menopause or during post-menopause period, most women suffered from menopausal symptoms irritability like ...
Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocr ...
As you probably know, sex hormone in women is declining with age. Men also experiencing the same, even though the declining rat ...
Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocr ...
The accurate diagnosis of endocrine dysfunction in the elderly requires a high index of suspicion. Signs and symptoms of hormone de ...
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There are several important changes in pharmacokinetics metabolism associated with aging that predispose the elderly to increased risk of druginduced side effects including cardiac arrhythmia.
First, advanced age is accompanied by a decrease in overall body weight, total body water, lean body mass, and intravascular volume, resulting in a greater volume of distribution (V d ), which is defined by the drug dose divided by drug plasma concentration (V d = dose/concentration). The reduced distribution volume will, therefore, lead to a higher drug concentration after a given dose in the elderly compared to the younger population. (more…)
Pharmacodynamics describes the course of action of a drugs and aging at the effector organ level, in terms of duration and magnitud ...
Complications of Adverse Drug Reactions may include hospitalization, increased hospital stays and health care expenditures, morbidi ...
Something you and your doctor should appreciate is that getting older influences the way you react to drugs. Elderly patients are t ...
The accurate diagnosis of endocrine dysfunction in the elderly requires a high index of suspicion. Signs and symptoms of hormone de ...
There are intrinsic changes in the cardiac pacemaker cells and the cardiac conduction system associated with aging, which increase ...
Mutations that extend lifespan in invertebrates typically render the animals resistant to multiple forms of lethal injury, whether the threat comes from oxidative agents, heat, heavy metals, or irradiation. Indeed, this stress resistance seems likely to represent the mechanism by which these mutations delay the aging process. Thus presumably much of the cellular and extracellular pathology that produces dysfunction and increases mortality risk in older animals is held in abeyance by the same, poorly defined, defenses that permit nematodes and flies to survive when exposed to external stress in an experimental setting. (more…)
Cellular Response to Oxidative Stress and Sensitivity of Transcription Factors to ROS That Determine the Response. It is establishe ...
The basic mechanisms of life and inheritance function much the same in worms, fruit flies, mice, and humans. That is one reason wh ...
The Late Biological Effects of Ionizing Radiation Exposure to ionizing radiation results in an increase in oxidative damage to DNA, ...
An increase in the concentration of free radicals, measured using electron spin resonance (ESR) spectroscopy, can reflect the degre ...
Many studies have shown that antibiotic drugs are often prescribed unnecessary or inappropriate. Drugs for elderly (geriatric d ...
