The prevalence of sexual dysfunction in women approaches 43%, and age is an important correlate. The underlying etiology of sexual dysfunction in women is complex. Nevertheless, hormonal changes such as loss of estrogens and androgens contribute significantly to some of the sexual difficulties experienced by aging women. (more…)

Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocrine function. Several mechanisms interact in most systems to bring about the observed changes. Aging is associated with anatomic changes of the endocrine glands. In addition, with age, changes in hormone secretion occur, including alterations in circadian or seasonal biorhythms, changes in pulsatile frequency or amplitude of hormone secretion, as well as absolute changes in mean serum hormonal levels. (more…)

The accurate diagnosis of endocrine dysfunction in the elderly requires a high index of suspicion. Signs and symptoms of hormone deficiency or excess may be absent. When such signs and symptoms are present, coexisting malnutrition or chronic disease may often make their interpretation difficult. (more…)

Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocrine function. Several mechanisms interact in most systems to bring about the observed changes. Aging is associated with anatomic changes of the endocrine glands. In addition, with age, changes in hormone replacement secretion occur, including alterations in circadian or seasonal biorhythms, changes in pulsatile frequency or amplitude of growth hormone secretion, as well as absolute changes in mean serum hormonal levels. The three main hormone systems that show decline with age are the gonadal hormones (menopause and andropause), the adrenal steroids DHEA and DHEA-S (adrenopause), and the GH/IGF-1 axis (somatopause). (more…)

Depression in late life is closely linked with senescence at a very basic level. Before discussing medical illness and disease processes, however, it will be helpful to review some more basic processes that may trigger, or at the very least exacerbate, depression through biochemical or neuroanatomical mechanisms. (more…)

For trained physicians, aging is often defined by the age-related diseases and disorders people experience as they grow older. In fact, aging is often portrayed as a disease that is amenable to treatment, just like any other elderly chronic diseases that physicians are trained to diagnose and treat. This is not an unexpected view of aging given the Western disease-oriented model of medical education. Examples of the conditions that anti-aging practitioners endeavor to treat or postpone include cardiovascular disease, cancer, sensory impairments, muscle and bone loss, loss of skin elasticity, and decline in sexual activity in elderly function. (more…)

Many clinical features of hypothyroidism are commonly found in the elderly, despite negligible changes in plasma thyroid hormone levels. These symptoms may reflect the decreased intracellular uptake of T 3 and alterations in gene activation/deactivation that are observed with aging. (more…)

HGH is the current buzz word in anti aging circles. It has gained wide media coverage and is being hailed as the ultimate in anti aging treatments with a whole lot of people claiming it to be the Elixir of Youth.

Human growth hormone naturally occurs in your body and is produced by the pituitary gland that is located in your brain. As the name suggests, it helps human grow. (more…)

You can easily address the causes of skin aging and skin greasiness, with the right skincare products. This article looks at the things that contribute to excessive oiliness and the things that can reduce it. Let’s start with the contributing factors.

Many cleansers, lotions, shampoos and other cosmetics contain mineral oil or petrolatum. These cause a greasy feeling, because they are not absorbed. They can also cause blemishes and pimples, (more…)

The largest single risk factor for developing cancer is age. The incidence of cancer increases exponentially with age, although death from cancer (cancer mortality) may decline at very old age. The inevitable age-dependent rise in cancer incidence is a feature of multicellular organisms that contain a substantial fraction of mitotic cells. Organisms such as flies and worms are composed primarily of post-mitotic cells, and hence do not develop cancer. (more…)