The prevalence of sexual dysfunction in women approaches 43%, and age is an important correlate. The underlying etiology of sexual dysfunction in women is complex. Nevertheless, hormonal changes such as loss of estrogens and androgens contribute significantly to some of the sexual difficulties experienced by aging women. (more…)

Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocrine function. Several mechanisms interact in most systems to bring about the observed changes. Aging is associated with anatomic changes of the endocrine glands. In addition, with age, changes in hormone secretion occur, including alterations in circadian or seasonal biorhythms, changes in pulsatile frequency or amplitude of hormone secretion, as well as absolute changes in mean serum hormonal levels. (more…)

The accurate diagnosis of endocrine dysfunction in the elderly requires a high index of suspicion. Signs and symptoms of hormone deficiency or excess may be absent. When such signs and symptoms are present, coexisting malnutrition or chronic disease may often make their interpretation difficult. (more…)

Altered cellular metabolism and intracellular and intercellular signaling with advancing age result in widespread changes in endocrine function. Several mechanisms interact in most systems to bring about the observed changes. Aging is associated with anatomic changes of the endocrine glands. In addition, with age, changes in hormone replacement secretion occur, including alterations in circadian or seasonal biorhythms, changes in pulsatile frequency or amplitude of growth hormone secretion, as well as absolute changes in mean serum hormonal levels. The three main hormone systems that show decline with age are the gonadal hormones (menopause and andropause), the adrenal steroids DHEA and DHEA-S (adrenopause), and the GH/IGF-1 axis (somatopause). (more…)

For trained physicians, aging is often defined by the age-related diseases and disorders people experience as they grow older. In fact, aging is often portrayed as a disease that is amenable to treatment, just like any other elderly chronic diseases that physicians are trained to diagnose and treat. This is not an unexpected view of aging given the Western disease-oriented model of medical education. Examples of the conditions that anti-aging practitioners endeavor to treat or postpone include cardiovascular disease, cancer, sensory impairments, muscle and bone loss, loss of skin elasticity, and decline in sexual activity in elderly function. (more…)

Many clinical features of hypothyroidism are commonly found in the elderly, despite negligible changes in plasma thyroid hormone levels. These symptoms may reflect the decreased intracellular uptake of T 3 and alterations in gene activation/deactivation that are observed with aging. (more…)

Involuntary weight loss is the result of many chronic progressive diseases, often leading to diminished lean body mass, frailty, susceptibility to illness, and increased mortality. Various anabolic agents have been used to combat weight loss with mixed results. Similar to the frustration experienced by advocates of weight loss in the obese, none of the pharmacological appetite stimulants available at the current time have been uniformly successful in combating involuntary weight loss in the elderly population. (more…)

The systemic benefits of exogenous Growth Hormone therapy in the healthy elderly remain unclear and controversial. Studies have not been able to demonstrate a clear anabolic effect of replacement of Growth Hormone in elderly subjects, possibly because Growth Hormone replacement cannot completely correct the alterations in binding recommended proteins. (more…)

There are new strategies to address the 3 critical factors for body health: blood sugar, insulin and inflammation. These formula guarantees that we will not get obese and be lean for life. Inflammation and obesity has relation that can be describing when we eat foods, it immediately causes high of blood sugar to drop, but then again it creates higher levels of the hormone insulin, which causes inflammation. (more…)

Everybody wants to stay healthy at any age, but this is something we wanted to have over a lifetime. But you can still begin applying healthful practices at any stage of your life to increase your probability of longer survival and having a better healthier body. Don’t take too much concern at your current age, because you can still receive many health benefits at any age. But the earlier you begin, the greater your results will likely be. (more…)